The glycoprotein D (US6) homolog is not essential for oncogenicity or horizontal transmission of Marek's disease virus

被引：31

作者：

Anderson, AS ^{[1
]}

Parcells, MS ^{[1
]}

Morgan, RW ^{[1
]}

机构：

[1] Univ Delaware, Dept Anim & Food Sci, Delaware Agr Expt Stn, Coll Agr Sci, Newark, DE 19717 USA

来源：

JOURNAL OF VIROLOGY | 1998年 / 72卷 / 03期

关键词：

D O I：

10.1128/JVI.72.3.2548-2553.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

RB1BUS6lacgpt, a Marek's disease virus (MDV) mutant having a disrupted glycoprotein D (go) homolog gene, established infection and induced tumors in chickens exposed to it by inoculation or by contact. Lymphoblastoid cell lines derived from RB1BUS6lacgpt-induced tumors harbored only the mutant virus. These results provide strong evidence that an intact go homolog gene is not essential for oncogenicity or horizontal transmission of MDV.

引用

页码：2548 / 2553

页数：6

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