Would SYNTAX have been a positive trial if XIENCE V had been used instead of TAXUS? A meta-analysis of a first-generation vs. a second-generation drug-eluting stent system

被引：24

作者：

Claessen, B. E. ^{[1
]}

Stone, G. W. ^{[2
,3
]}

Smits, P. C. ^{[4
]}

Kedhi, E. ^{[4
]}

Kikkert, W. J. ^{[1
]}

Piek, J. J. ^{[1
]}

Henriques, J. P. S. ^{[1
]}

机构：

[1] Acad Med Ctr, Dept Cardiol, NL-1100 DD Amsterdam, Netherlands

[2] Columbia Univ, Med Ctr, New York, NY USA

[3] Cardiovasc Res Fdn, New York, NY USA

[4] Maasstad Hosp, Dept Cardiol, Rotterdam, Netherlands

来源：

NETHERLANDS HEART JOURNAL | 2010年 / 18卷 / 09期

关键词：

Percutaneous Coronary Intervention; Coronary Artery Bypass Surgery; Drug Eluting Stents; Coronary Artery Disease; Meta-analysis; CORONARY-ARTERY-DISEASE;

D O I：

10.1007/BF03091813

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Treatment options for coronary revascularisation include percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). In the 'synergy between PCI with TAXUS and cardiac surgery (SYNTAX)' trial, PCI and CABG using state-of-the-art techniques (using paclitaxel-eluting stents and arterial grafts, respectively) were compared in the treatment of complex coronary artery disease. In Syntax, PCI was inferior to CABG at one year, entirely due to an increased repeat intervention rate. We hypothesised that the use of a superior drug-eluting stent system could reduce the need for repeat intervention. (Neth Heart J 2010;18:451-3.)

引用

页码：451 / 453

页数：3

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