Reactions of pyrazolium salts with silyllithium reagents.: Regioselective synthesis of 5-silylated 3-pyrazolines

被引：14

作者：

Cuadrado, P ^{[1
]}

González-Nogal, AM ^{[1
]}

机构：

[1] Univ Valladolid, Dept Quim Organ, Valladolid 47011, Spain

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 11期

关键词：

D O I：

10.1016/S0040-4039(97)10825-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3,5-trisubstituted-2-methylpyrazolium iodides react with dimethylphenylsilyl- and tert-butyldiphenylsilyllithium leading, in general, to one of the corresponding 5-silyl-3-pyrazolines. The silyl group is easily substituted by electrophiles to give 5-functionalized 3-pyrazolines. Moreover, 5-silyl-3-pyrazolines undergo thermic ring opening with silicon-rearrangement affording alpha-silylated beta-diimines. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1449 / 1452

页数：4