Peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease

被引:231
作者
Finck, Brian N.
Kelly, Daniel P.
机构
[1] Washington Univ, Sch Med, Ctr Human Nutr, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Cardiovasc Res Ctr, St Louis, MO 63110 USA
[3] Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA
[4] Washington Univ, Sch Med, Dept Mol Biol & Pharmacol, St Louis, MO 63110 USA
[5] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
关键词
cardiomyopathy; cardiovascular diseases; diabetes mellitus; fatty acids; genes; glucose; metabolism;
D O I
10.1161/CIRCULATIONAHA.107.670588
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:2540 / 2548
页数:9
相关论文
共 100 条
[1]   PGC-l-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells [J].
Andersson, U ;
Scarpulla, RC .
MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (11) :3738-3749
[2]   Common polymorphisms of the PPAR-γ2 (Pro12Ala) and PGC-1α (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial [J].
Andrulionytè, L ;
Zacharova, J ;
Chiasson, JL ;
Laakso, M .
DIABETOLOGIA, 2004, 47 (12) :2176-2184
[3]   Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle [J].
Arany, Z ;
He, HM ;
Lin, JD ;
Hoyer, K ;
Handschin, C ;
Toka, O ;
Ahmad, F ;
Matsui, T ;
Chin, S ;
Wu, PH ;
Rybkin, II ;
Shelton, JM ;
Manieri, M ;
Cinti, S ;
Schoen, FJ ;
Bassel-Duby, R ;
Rosenzweig, A ;
Ingwall, JS ;
Spiegelman, BM .
CELL METABOLISM, 2005, 1 (04) :259-271
[4]   Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-γ coactivator 1α [J].
Arany, Zoltan ;
Novikov, Mikhail ;
Chin, Sherry ;
Ma, Yanhong ;
Rosenzweig, Anthony ;
Spiegelman, Bruce M. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (26) :10086-10091
[5]   Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1 [J].
Baar, K ;
Wende, AR ;
Jones, TE ;
Marison, M ;
Nolte, LA ;
Chen, M ;
Kelly, DP ;
Holloszy, JO .
FASEB JOURNAL, 2002, 16 (14) :1879-1886
[6]   Deactivation of peroxisome proliferator-activated receptor-α during cardiac hypertrophic growth [J].
Barger, PM ;
Brandt, JM ;
Leone, TC ;
Weinheimer, CJ ;
Kelly, DP .
JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (12) :1723-1730
[7]   PPAR signaling in the control of cardiac energy metabolism [J].
Barger, PM ;
Kelly, DP .
TRENDS IN CARDIOVASCULAR MEDICINE, 2000, 10 (06) :238-245
[8]  
BENNETT M J, 1991, Pediatric Pathology, V11, P889
[9]   Inborn errors of mitochondrial fatty acid oxidation [J].
Bennett, MJ ;
Rinaldo, P ;
Strauss, AW .
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 2000, 37 (01) :1-44
[10]   Role of the β3-adrenergic receptor and/or a putative β4-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-γ coactivator-1 [J].
Boss, O ;
Bachman, E ;
Vidal-Puig, A ;
Zhang, CY ;
Peroni, O ;
Lowell, BB .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 261 (03) :870-876