MULTIVALENT LECTIN-CARBOHYDRATE INTERACTIONS: ENERGETICS AND MECHANISMS OF BINDING

被引：97

作者：

Dam, Tarun K. ^{[1
]}

Brewer, C. Fred ^{[2
]}

机构：

[1] Albert Einstein Coll Med, Dept Mol Pharmacol, Bronx, NY 10461 USA

[2] Albert Einstein Coll Med, Dept Mol Pharmacol Microbiol & Immunol, Bronx, NY 10461 USA

来源：

ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL 63 | 2010年 / 63卷

关键词：

PORCINE SUBMAXILLARY MUCIN; CONCANAVALIN-A; THERMODYNAMIC ANALYSIS; T-CELLS; GLYCOSYLATION; APOPTOSIS; GALECTIN-1; RECEPTOR; CANCER; OLIGOSACCHARIDES;

D O I：

10.1016/S0065-2318(10)63005-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：139 / 164

页数：26

共 61 条

[1]

Akahani S, 1997, CANCER RES, V57, P5272

[2] Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions [J].

Brewer, CF ;

Miceli, MC ;

Baum, LG .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2002, 12 (05) :616-623

[3] Mucins and mucin binding proteins in colorectal cancer [J].

Byrd, JC ;

Bresalier, RS .

CANCER AND METASTASIS REVIEWS, 2004, 23 (1-2) :77-99

[4] Amino acid sequence, glycan structure, and proteolytic processing of the lectin of Vatairea macrocarpa seeds [J].

Calvete, JJ ;

Santos, CF ;

Mann, K ;

Grangeiro, TB ;

Nimtz, M ;

Urbanke, C ;

Cavada, BS .

FEBS LETTERS, 1998, 425 (02) :286-292

[5]

CARLSON DM, 1968, J BIOL CHEM, V243, P616

[6] Binding studies of α-GaINAc-specific lectins to the α-GaINAc (Tn-antigen) form of porcine submaxillary mucin and its smaller fragments [J].

Dam, Tarun K. ;

Gerken, Thomas A. ;

Cavada, Benildo S. ;

Nascimento, Kyria S. ;

Moura, Tales R. ;

Brewer, C. Fred .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (38) :28256-28263

[7] Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants [J].

Dam, TK ;

Gabius, HJ ;

André, S ;

Kaltner, H ;

Lensch, M ;

Brewer, CF .

BIOCHEMISTRY, 2005, 44 (37) :12564-12571

[8]

Dam TK, 2004, METHOD ENZYMOL, V379, P107

[9]

Dam TK, 2003, METHOD ENZYMOL, V362, P455

[10] Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry [J].

Dam, TK ;

Brewer, CF .

CHEMICAL REVIEWS, 2002, 102 (02) :387-429

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