Psychological effects of a suspicious prostate cancer screening test followed by a benign biopsy result

被引:80
作者
McNaughton-Collins, M
Fowler, FJ
Caubet, JF
Bates, DW
Lee, JM
Hauser, A
Barry, MJ
机构
[1] Massachusetts Gen Hosp, Gen Med Div, Boston, MA 02114 USA
[2] Univ Massachusetts, Ctr Survey Res, Boston, MA 02125 USA
[3] Brigham & Womens Hosp, Gen Med Div, Boston, MA 02115 USA
[4] Boston Med Ctr, Gen Med Div, Boston, MA USA
关键词
D O I
10.1016/j.amjmed.2004.06.036
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
PURPOSE: To evaluate the psychological implications of an apparently false-positive screening result for prostate cancer. METHODS: The sample comprised 167 men with a benign biopsy result in response to a Suspicious screening test result (biopsy group) and 233 men with a normal prostate-specific antigen (PSA) test result (control group). The men responded to a questionnaire within about 6 weeks of their biopsy or PSA results. They were asked about demographic characteristics, medical history, psychological effects, biopsy experience, and prostate cancer knowledge. RESULTS: The survey response rate was 85% (400/471). The mean (+/- SD) age of respondents was 60 +/- 9 years (range, 40 to 88 years); 88% (n = 350) were white. Forty-nine percent (81/167) of men in the biopsy group reported having thought about prostate cancer either "a lot" or "some of the time", compared with 18% (42/230) in the control group (P < 0.001). In addition, 40% (67/167) in the biopsy group reported having worried "a lot" or "some of the time" that they may develop prostate cancer, compared with 8% (18/231) in the control group (P < 0.001). CONCLUSION: Men who underwent prostate biopsy more often reported having thought and worried about prostate cancer, despite having received a benign result. This underrecognized human cost of screening should be considered in the debate about the benefits and harms of prostate cancer screening. (C) 2004 by Elsevier Inc.
引用
收藏
页码:719 / 725
页数:7
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