IR-spectral signatures of aromatic-sugar complexes: Probing carbohydrate-protein interactions

被引：91

作者：

Screen, James

Stanca-Kaposta, E. Cristina

Gamblin, David P.

Liu, Bo

Macleod, Neil A.

Snoek, Lavina C.

Davis, Benjamin G.

Simons, John P.

机构：

[1] Univ Oxford, Dept Chem, Phys & Theoret Chem Lab, Oxford OX1 3QZ, England

[2] Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 20期

基金：

英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会;

关键词：

carbohydrates; density functional calculations; molecular recognition; vibrational spectroscopy;

D O I：

10.1002/anie.200605116

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Key interactions: Sugar-arene complexes have been created in molecular-beam experiments and observed by IR ion-dip spectroscopy in the gas phase. These complexes are powerful models of the selective recognition seen in protein-sugar complexes, for example between the galactose-specific lectin from Artocarpus hirsute and MeGal (see picture). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：3644 / 3648

页数：5

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