WITHIN-HOUSEHOLD SHARING OF A FLUOROQUINOLONE-RESISTANT ESCHERICHIA COLI SEQUENCE TYPE ST131 STRAIN CAUSING PEDIATRIC OSTEOARTICULAR INFECTION

被引:40
作者
Johnson, James R. [1 ,2 ]
Anderson, John T. [3 ]
Clabots, Connie [1 ,2 ]
Johnston, Brian [1 ,2 ]
Cooperstock, Michael [4 ]
机构
[1] Vet Affairs Med Ctr, Infect Dis Sect, Minneapolis, MN USA
[2] Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA
[3] Childrens Mercy Hosp, Dept Orthopaed Surg, Kansas City, MO 64108 USA
[4] Univ Missouri, Sch Med, Dept Child Hlth, Columbia, MO USA
关键词
Escherichia coli infections; ST131; transmission; septic arthritis; fluoroquinolone resistance; COLONIZATION PATTERNS; MEMBERS; VIRULENCE; CTX-M-15;
D O I
10.1097/INF.0b013e3181c89bd7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A fluoroquinolone-resistant Escherichia coli strain of sequence type ST131 caused severe septic arthritis and contiguous osteomyelitis in an 8-month-old girl, and colonized the girl's healthy mother, who shared a different fecal E. coli strain with the father. Within-household transmission can contribute to the dissemination of the emerging, multidrug-resistant ST131 clonal group, which has evident invasive potential for otherwise-healthy children.
引用
收藏
页码:473 / 475
页数:3
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