Asymmetric reduction of enantiopure imines with zinc borohydride: stereoselective synthesis of chiral amines

被引：44

作者：

Cimarelli, C ^{[1
]}

Palmieri, G ^{[1
]}

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(00)00209-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The first application of zinc borohydride in the reduction of enantiopure imines for the stereoselective preparation of both the enantiomers of secondary amines is described. A possible explanation of the stereoselectivity and of the reaction mechanism is suggested on the basis of theoretical calculations. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2555 / 2563

页数：9

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