History, present status and future of sentinel node biopsy in breast cancer - The Mary Beves lecture

被引:13
作者
Mansel, RE [1 ]
Khonji, NI [1 ]
Clarke, D [1 ]
机构
[1] Univ Dept Surg, Cardiff CF14 4XN, S Glam, Wales
关键词
D O I
10.1080/028418600750012998
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The word 'Sentinel' is defined in The Oxford English Dictionary as 'a guard, one who keeps watch or a sentry'. When translated to the concept of a tumour and its lymph node drainage, the sentinel node could be interpreted to mean the lymph node that guards or keeps watch over a tumour. The sentinel lymph node can thus be defined as the first lymph node that drains a primary tumour within the regional lymphatic basin of that tumour. We know that tumour progression in breast cancer often occurs in an orderly, progressive fashion (1, 2). So in theory, if the sentinel node is tumour free then the rest of the nodes in the lymphatic basin should also be uninvolved by the tumour.
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页码:265 / 268
页数:4
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