Molecular cloning of human caveolin 3

被引:12
作者
Biederer, C [1 ]
Ries, S [1 ]
Drobnik, W [1 ]
Schmitz, G [1 ]
机构
[1] Univ Regensburg, Inst Clin Chem & Lab Med, D-93042 Regensburg, Germany
来源
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE | 1998年 / 1406卷 / 01期
关键词
caveolin; caveolae; raft; skeletal muscle; cDNA sequence; RACE-PCR;
D O I
10.1016/S0925-4439(97)00095-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We isolated a full-length cDNA encoding human caveolin 3, which is 72% and 59% homologous to human caveolin 1 and caveolin 2, respectively. Human caveolin 3 protein contains the 'caveolin signature sequence' and the 33 amino acids spanning intramembrane domain common to all caveolins. Northern blot analysis indicates that the caveolin 3 transcript is 1.6 kb in size and exclusively detectable in muscle tissue. (C) 1998 Elsevier Science B.V.
引用
收藏
页码:5 / 9
页数:5
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