Regulation of the chitobiose-phosphotransferase system in Vibrio cholerae

被引:26
作者
Berg, Thorsten [1 ]
Schild, Stefan [1 ]
Reidl, Joachim [1 ]
机构
[1] Univ Wurzburg, Inst Hyg & Mikrobiol, D-97080 Wurzburg, Germany
关键词
chitosan; chitobiose; Vibrio cholerae; chs operon;
D O I
10.1007/s00203-006-0207-4
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Vibrio cholerae harbours a phosphotransferase system (PTS) enabling the organism to utilise chitosan oligosaccharide, e.g. derived from deacetylated chitin. As shown recently, this utilization system is encoded by the ORFs VC1281-1283 (Meibom et al. in Proc Natl Acad Sci USA, 101:2524-2529, 2004). By using a transcriptional reporter fusion technique, we identified the regulator of the system and characterised gene expression. Furthermore, we found that gene expression of this PTS system is influenced by catabolite regulation and also by an Mlc homologue (VC2007), which in E. coli is a global regulator of sugar metabolism.
引用
收藏
页码:433 / 439
页数:7
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