Outdoor exercise reduces the risk of hypovitaminosis D in the obese

被引:79
作者
Florez, Hermes
Martinez, Ramon
Chacra, Walid
Strickman-Stein, Nancy
Levis, Silvina
机构
[1] Univ Miami, Miami, FL 33101 USA
[2] Univ Miami, Sch Med, Miami, FL 33136 USA
[3] Jackson Mem Hosp, Miami, FL 33136 USA
[4] Miami Vet Affairs Med Ctr, GRECC, Miami, FL 33136 USA
关键词
vitamin D; hypovitaminosis D; obesity; minority; Hispanics; exercise;
D O I
10.1016/j.jsbmb.2006.12.032
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
Obesity is associated with lower levels of serum 25-hydroxyvitamin D (25(OH)D). Obese individuals might need higher doses of vitamin D supplementation than the general Population. In this cross-sectional study, associations between 25(OH)D serum levels, body mass index (BMI). and outdoor exercise were assessed in a population of 291 ambulatory patients attending the Osteoporosis Center at the University of Miami, mean age 62 +/- 13.48 years. Obesity was defined as BMI >= 30 kg/m(2) and hypovitaminosis D as 25(OH)D <= 30 ng/ml. Overall, prevalence of obesity was 14.1% and of hypovitaminosis D was 42.4%. Among Hispanics, there was a significantly higher prevalence of hypovitaminosis D in obese (63.2%) compared to non-obese individuals (35.8%). Outdoor exercise had a significant effect on the prevalence of hypovitaminosis D in Hispanics, with a lower prevalence in those performing outdoor exercise (24.1%) compared to those who did not (47.9%). After adjusting for age, gender, and ethnicity, those reporting outdoor exercise were 47% less likely to have hypovitaminosis D, while those with obesity had more than twice the risk. Since outdoor exercise may protect overweight individuals from hypovitaminosis D, prevention programs involving higher doses of vitamin D and/or outdoor exercise may result in additional metabolic and functional benefits in this population. (c) 2007 Published by Elsevier Ltd.
引用
收藏
页码:679 / 681
页数:3
相关论文
共 10 条
[1]
Body fat content and 25-hydroxyvitamin D levels in healthy women [J].
Arunabh, S ;
Pollack, S ;
Yeh, J ;
Aloia, JF .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (01) :157-161
[2]
EVIDENCE THAT 1,25-DIHYDROXYVITAMIN-D-3 INHIBITS THE HEPATIC PRODUCTION OF 25-HYDROXYVITAMIN-D IN MAN [J].
BELL, NH ;
SHAW, S ;
TURNER, RT .
JOURNAL OF CLINICAL INVESTIGATION, 1984, 74 (04) :1540-1544
[3]
EVIDENCE FOR ALTERATION OF THE VITAMIN-D-ENDOCRINE SYSTEM IN OBESE SUBJECTS [J].
BELL, NH ;
EPSTEIN, S ;
GREENE, A ;
SHARY, J ;
OEXMANN, MJ ;
SHAW, S .
JOURNAL OF CLINICAL INVESTIGATION, 1985, 76 (01) :370-373
[4]
Estimates of optimal vitamin D status [J].
Dawson-Hughes, B ;
Heaney, RP ;
Holick, MF ;
Lips, P ;
Meunier, PJ ;
Vieth, R .
OSTEOPOROSIS INTERNATIONAL, 2005, 16 (07) :713-716
[5]
LOW CIRCULATING VITAMIN-D IN OBESITY [J].
LIEL, Y ;
ULMER, E ;
SHARY, J ;
HOLLIS, BW ;
BELL, NH .
CALCIFIED TISSUE INTERNATIONAL, 1988, 43 (04) :199-201
[6]
DISTRIBUTION AND STORAGE OF VITAMIN-D AND ITS METABOLITES IN HUMAN TISSUES [J].
MAWER, EB ;
STANBURY, SW ;
BACKHOUSE, J ;
HOLMAN, CA ;
LUMB, GA .
CLINICAL SCIENCE, 1972, 43 (03) :413-+
[7]
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001 [J].
Mokdad, AH ;
Ford, ES ;
Bowman, BA ;
Dietz, WH ;
Vinicor, F ;
Bales, VS ;
Marks, JS .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (01) :76-79
[8]
SERUM 25-HYDROXYVITAMIN D-3 IS RELATED TO PHYSICAL-ACTIVITY AND ETHNICITY BUT NOT OBESITY IN A MULTICULTURAL WORKFORCE [J].
SCRAGG, R ;
HOLDAWAY, I ;
SINGH, V ;
METCALF, P ;
BAKER, J ;
DRYSON, E .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1995, 25 (03) :218-223
[9]
Decreased bioavailability of vitamin D in obesity [J].
Wortsman, J ;
Matsuoka, LY ;
Chen, TC ;
Lu, ZR ;
Holick, MF .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2000, 72 (03) :690-693
[10]
ZADSHIRA, 2005, ETHNIC DIS, V15, pS5