HEMATOLOGY Are macrophages the bad guys in Hodgkin lymphoma?

被引：16

作者：

Diehl, Volker ^{[1
]}

机构：

[1] Univ Cologne, Dept Internal Med Hematol Oncol, D-50924 Cologne, Germany

来源：

NATURE REVIEWS CLINICAL ONCOLOGY | 2010年 / 7卷 / 06期

关键词：

SURVIVAL; DISEASE;

D O I：

10.1038/nrclinonc.2010.71

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Prognostic models for patients with Hodgkin lymphoma are imperfect and do not allow a precise individualized therapy. A recent gene-expression profiling study, translated into a routine immunohistological test, identified genes of tumor-associated macrophages as being responsible for treatment outcome in patients with Hodgkin lymphoma. If this finding is confirmed by other investigators, it could be a major step towards personalized therapy for patients with Hodgkin lymphoma.

引用

页码：301 / 302

页数：2

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