Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2

被引：54

作者：

Gane, E. ^{[1
]}

Kershenobich, D. ^{[2
]}

Seguin-Devaux, C. ^{[3
]}

Kristian, P. ^{[4
]}

Aho, I. ^{[5
]}

Dalgard, O. ^{[6
]}

Shestakova, I. ^{[7
,8
]}

Nymadawa, P. ^{[9
]}

Blach, S. ^{[10
]}

Acharya, S. ^{[11
]}

Anand, A. C. ^{[12
]}

Andersson, M. I. ^{[13
]}

Arendt, V. ^{[14
,15
]}

Arkkila, P. ^{[16
]}

Baatarkhuu, O. ^{[17
]}

Barclay, K. ^{[18
]}

Ben-Ari, Z. ^{[19
,20
]}

Bergin, C. ^{[21
,22
]}

Bessone, F. ^{[23
]}

Blokhina, N. ^{[24
]}

Brunton, C. R. ^{[25
]}

Choudhuri, G. ^{[26
]}

Chulanov, V. ^{[27
]}

Cisneros, L. ^{[28
]}

Croes, E. A. ^{[29
]}

Dahgwahdorj, Y. A. ^{[30
]}

Daruich, J. R. ^{[31
]}

Dashdorj, N. R. ^{[32
]}

Davaadorj, D. ^{[33
]}

de Knegt, R. J. ^{[34
]}

de Vree, M. ^{[35
]}

Gadano, A. C. ^{[36
]}

Gower, E. ^{[10
]}

Halota, W. ^{[37
]}

Hatzakis, A. ^{[38
]}

Henderson, C. ^{[39
]}

Hoffmann, P. ^{[40
]}

Hornell, J. ^{[18
]}

Houlihan, D. ^{[41
]}

Hrusovsky, S. ^{[42
,43
]}

Jarcuska, P. ^{[44
]}

Kostrzewska, K. ^{[45
]}

Leshno, M. ^{[46
]}

Lurie, Y. ^{[47
]}

Mahomed, A. ^{[48
]}

Mamonova, N. ^{[49
]}

Mendez-Sanchez, N. ^{[50
]}

Mossong, J. ^{[51
]}

Norris, S. ^{[21
]}

Nurmukhametova, E. ^{[24
]}

机构：

[1] Auckland Hosp, Clin Studies Unit, Auckland, New Zealand

[2] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Tlalpan, Mexico

[3] Ctr Rech Publ Sante, Lab Retrovirol, Strassen, Luxembourg

[4] Safarik Univ, Fac Med, Dept Infectol & Travel Med, Kosice, Slovakia

[5] Univ Helsinki, Cent Hosp, Dept Infect Dis, Helsinki, Finland

[6] Akershus Univ Hosp, Dept Infect Dis, Oslo, Norway

[7] Moscow State Univ Med & Dent, Dept Infect Dis & Epidemiol, Moscow, Russia

[8] Minist Hlth Russian Federat, Moscow, Russia

[9] Mongolian Acad Med Sci, Ulaanbaatar, Mongolia

[10] CDA, Louisville, CO USA

[11] All India Inst Med Sci, Dept Gastroenterol, New Delhi, India

[12] Indraprastha Apollo Hosp, Indian Natl Assoc Study Liver, HCV Task Force, New Delhi, India

[13] Univ Stellenbosch, Dept Pathol, Fac Hlth Sci, Div Med Virol, ZA-7600 Stellenbosch, South Africa

[14] Ctr Hosp Luxembourg, Luxembourg, Luxembourg

[15] Ctr Rech Publ Sante, Strassen, Luxembourg

[16] Univ Helsinki, Cent Hosp, Dept Gastroenterol, Helsinki, Finland

[17] Mongolian Natl Univ Med Sci, Dept Infect Dis, Ulaanbaatar, Mongolia

[18] Hepatitis Fdn New Zealand, Whakatane, New Zealand

[19] Chaim Sheba Med Ctr, Liver Dis Ctr, IL-52621 Tel Hashomer, Israel

[20] Tel Aviv Univ, Sackler Sch Med, IL-69978 Tel Aviv, Israel

[21] St James Hosp, Dublin 8, Ireland

[22] Trinity Coll Dublin, Dublin, Ireland

[23] Univ Nacl Rosario, Sch Med, RA-2000 Rosario, Argentina

[24] Hosp Infect Dis 1, Moscow, Russia

[25] Canterbury Dist Hlth Board, Canterbury, New Zealand

[26] Fortis Mem Res Inst, Dept Gastroenterol & Hepatobiliary Sci, Gurgaon, Haryana, India

[27] Minist Publ Hlth Russia, Cent Res Inst Epidemiol, Reference Ctr Viral Hepatitis, Moscow, Russia

[28] Inst Mexicano Seguro Social, UMAE 25, Monterrey, NL, Mexico

[29] Trimbos Inst, Utrecht, Netherlands

[30] Mongolian Natl Univ Med Sci, Ulaanbaatar, Mongolia

[31] Univ Buenos Aires, Hosp Clin San Martin, Secc Hepatol, Buenos Aires, DF, Argentina

[32] Onom Fdn, Ulaanbaatar, Mongolia

[33] Mongolian Natl Univ Med Sci, Dept Gastroenterol & Hepatol, Ulaanbaatar, Mongolia

[34] Erasmus MC Univ Med Ctr, Dept Gastroenterol & Hepatol, Rotterdam, Netherlands

[35] Univ Groningen, Univ Med Ctr Groningen, NL-9713 AV Groningen, Netherlands

[36] Italian Hosp Buenos Aires, Buenos Aires, DF, Argentina

[37] CMUMK Bydgoszcz, Dept Infect Dis & Hepatol, Bydgoszcz, Poland

[38] Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, GR-11527 Athens, Greece

[39] New Zealand Needle Exchange Programme, Christchurch, New Zealand

[40] Hlth Directorate, Luxembourg, Luxembourg

[41] St Vincents Univ Hosp, Dublin 4, Ireland

[42] SZU, Dept Internal Med 1, Bratislava, Slovakia

[43] Fac Med, Clin Infect Dis, Kosice, Slovakia

[44] Safarik Univ, Fac Med, Dept Internal Med 1, Kosice, Slovakia

[45] HTA Consulting, Krakow, Poland

[46] Tel Aviv Univ, IL-69978 Tel Aviv, Israel

[47] Shaarey Zedek Med Ctr, Liver Unit, Jerusalem, Israel

[48] Univ Witwatersrand, Dept Internal Med, Johannesburg, South Africa

[49] Clin Diagnost & Res Ctr, Moscow, Russia

[50] Med Clin & Fdn, Liver Res Unit, Mexico City, DF, Mexico

来源：

JOURNAL OF VIRAL HEPATITIS | 2015年 / 22卷

关键词：

diagnosis; disease burden; epidemiology; HCV; hepatitis C; incidence; mortality; prevalence; scenarios; treatment; HEPATOCELLULAR-CARCINOMA; LIVER-TRANSPLANTATION; EXPERIENCE; MONTERREY; RISK; UMAE;

D O I：

10.1111/jvh.12352

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries, and the relative impact of two scenarios was considered: (i) increased treatment efficacy while holding the treated population constant and (ii) increased treatment efficacy and increased annual treated population. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. In most countries, the annual treated population had to increase several fold to achieve the largest reductions in HCV-related morbidity and mortality. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. In most of the studied countries, the majority of patients were born between 1945 and 1985.

引用

页码：46 / 73

页数：28

共 37 条

[1] A Risk for Hepatocellular Carcinoma Persists Long-term After Sustained Virologic Response in Patients With Hepatitis C-Associated Liver Cirrhosis [J].

Aleman, Soo ;

Rahbin, Nogol ;

Weiland, Ola ;

Davidsdottir, Loa ;

Hedenstierna, Magnus ;

Rose, Nina ;

Verbaan, Hans ;

Stal, Per ;

Carlsson, Tony ;

Norrgren, Hans ;

Ekbom, Anders ;

Granath, Fredrik ;

Hultcrantz, Rolf .

CLINICAL INFECTIOUS DISEASES, 2013, 57 (02) :230-236

[2]

[Anonymous], NAT HEP C DAT INF AC

[3]

[Anonymous], J VIRAL HEP IN PRESS

[4]

[Anonymous], 2000, HEPATITIS C INFECT N

[5]

[Anonymous], HEP C

[6]

[Anonymous], FW13014 I ENV SCI RE

[7]

[Anonymous], ANAL REV

[8]

[Anonymous], 12 THL

[9] Predictors of response of US veterans to treatment for the hepatitis C virus [J].

Backus, Lisa I. ;

Boothroyd, Derek B. ;

Phillips, Barbara R. ;

Mole, Larry A. .

HEPATOLOGY, 2007, 46 (01) :37-47

[10]

Burguete-García AI, 2011, SALUD PUBLICA MEXICO, V53, pS7

← 1 2 3 4 →