Epidemiology of Hepatocellular Carcinoma

被引：1161

作者：

Lafaro, Kelly J. ^{[1
]}

Demirjian, Aram N. ^{[2
]}

Pawlik, Timothy M. ^{[3
]}

机构：

[1] Johns Hopkins Univ, Johns Hopkins Hosp, Sch Med, Dept Surg, Baltimore, MD 21287 USA

[2] Univ Calif Irvine, Dept Surg, Orange, CA 92868 USA

[3] Johns Hopkins Univ Hosp, Dept Surg, Div Surg Oncol, Baltimore, MD 21287 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2015年 / 24卷 / 01期

关键词：

Hepatocellular carcinoma; Chronic liver disease; Cirrhosis; Hepatitis B; Hepatitis C; Incidence; Risk factors; Aflatoxin; HEPATITIS-B-VIRUS; ALCOHOLIC LIVER-DISEASE; RISK-FACTORS; NATURAL-HISTORY; DIABETES-MELLITUS; CIGARETTE-SMOKING; UNITED-STATES; CANCER-RISK; P53; GENE; NONALCOHOLIC STEATOHEPATITIS;

D O I：

10.1016/j.soc.2014.09.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hepatocellular carcinoma (Hcc) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.

引用

页码：1 / +

页数：18

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