Y chromosome of D-pseudoobscura is not homologous to the ancestral Drosophila Y

被引：119

作者：

Carvalho, AB

Clark, AG

机构：

[1] Univ Fed Rio de Janeiro, Dept Genet, BR-21944970 Rio De Janeiro, Brazil

[2] Cornell Univ, Dept Mol Biol & Genet, Ithaca, NY 14853 USA

来源：

SCIENCE | 2005年 / 307卷 / 5706期

关键词：

D O I：

10.1126/science.1101675

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We report a genome-wide search of Y-linked genes in Drosophila pseudoobscura. All six identifiable orthologs of the D. melanogaster, Y-linked genes have autosomal inheritance in D. pseudoobscura. Four-orthologs were investigated in detail and proved to be Y-linked in D. guanche and D. bifasciata, which shows that less than 18 million years ago the ancestral Drosophila Y chromosome was translocated to an autosome in the D. pseudoobscura lineage. We found 15 genes and pseudogenes in the current Y of D. pseudoobscura, and none are shared with the D. melanogaster Y. Hence, the Y chromosome in the D. pseudoobscura lineage appears to have arisen de novo and is not homologous to the D. melanogaster Y.

引用

页码：108 / 110

页数：3

共 24 条

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