Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

被引：70

作者：

Lin, Po-Liang

Fang, Hsu-Wei

Tseng, Tiffany

Lee, Wun-Hsing

机构：

[1] Natl Taipei Univ Technol, Dept Chem Engn & Biotechnol, Taipei 106, Taiwan

[2] Natl Taipei Univ Technol, Grad Inst Mfg Technol, Taipei 106, Taiwan

[3] Natl Taipei Univ Technol, Inst Biotechnol, Taipei 106, Taiwan

来源：

MATERIALS LETTERS | 2007年 / 61卷 / 14-15期

关键词：

polylactic acid; hydroxyapatite; composite; mechanical strength; cell proliferation;

D O I：

10.1016/j.matlet.2006.10.064

中图分类号：

T [工业技术];

学科分类号：

08 [工学];

摘要：

Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：3009 / 3013

页数：5

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