Synthetic study of aquayamycin.: Part 1:: Synthesis of 3-(phenylsulfonyl)phthalides possessing a β-C-olivoside

被引：31

作者：

Matsumoto, T

Yamaguchi, H

Hamura, T

Tanabe, M

Kuriyama, Y

Suzuki, K ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Chem, Tokyo 1528551, Japan

[2] Japan Sci & Technol Corp, CREST, Tokyo 1528551, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 43期

关键词：

D O I：

10.1016/S0040-4039(00)01478-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthetic route to 3-(phenylsulfonyl)phthalides possessing a beta -C-olivoside was developed by exploiting the regioselective [2+2] cycloaddition of benzyne with ketene silyl acetal. The compounds are useful in the total synthesis of the angucyclines, including aquayamycin. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8383 / 8387

页数：5

共 19 条

[1] TOTAL SYNTHESIS OF THE ANGUCYCLINE ANTIBIOTICS URDAMYCINONE-B AND 104-2 VIA A COMMON SYNTHETIC INTERMEDIATE [J].