Synthesis of optically active C2-symmetric ketones for the asymmetric epoxidation of prochiral olefins by dioxiranes generated in situ with Caroate™ as a peroxide source

被引：69

作者：

Adam, W ^{[1
]}

Zhao, CG ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 24期

关键词：

D O I：

10.1016/S0957-4166(97)00559-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The new optically active C-2-symmetric ketones 3a (from mannitol) and 3b (from TADDOL) were prepared and the in-situ-generated dioxiranes (with Caroate(TM) as peroxide source) were shown to serve as effective oxidants for the asymmetric epoxidation tee values up to 81%) of prochiral trans and trisubstituted olefins. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：3995 / 3998

页数：4

共 19 条

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