Isolated meningeal chloroma (granulocytic sarcoma) - a case report and review of the literature

被引：37

作者：

Binder, C

Tiemann, M

Haase, D

Humpe, A

Kneba, M

机构：

[1] Univ Gottingen, Dept Hematol & Oncol, D-37075 Gottingen, Germany

[2] Univ Kiel, Inst Hematopathol, Kiel, Germany

[3] Univ Kiel, Med Clin 2, Kiel, Germany

来源：

ANNALS OF HEMATOLOGY | 2000年 / 79卷 / 08期

关键词：

chloroma; acute myeloblastic leukemia; chemotherapy; autologous stem cell transplantation;

D O I：

10.1007/s002770000165

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Isolated chloromas (granulocytic sarcomas) are rare tumors, most of them progressing to acute myeloblastic leukemia within months. There are still no conclusive treatment strategies for this entity; however, early antileukemic chemotherapy seems to lower the probability of developing systemic disease and prolong survival. We report on a patient with isolated meningeal chloroma, primarily misdiagnosed as a high-grade Non-Hodgkin's lymphoma. Two cycles of antileukemic induction chemotherapy were administered, followed by local irradiation and intensified consolidation therapy with autologous stem cell transplantation. After 20 months, he is still in complete remission.

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收藏

页码：459 / 462

页数：4

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