Inhaled corticosteroids and allergy specialty care reduce emergency hospital use for asthma

被引:70
作者
Schatz, M
Cook, EF
Nakahiro, R
Petitti, D
机构
[1] Kaiser Permanente Med Ctr, Dept Allergy, San Diego, CA 92111 USA
[2] Kaiser Permanente Med Ctr, Pharm Analyt Serv, San Diego, CA 92111 USA
[3] Kaiser Permanente Med Ctr, Dept Res & Evaluat, San Diego, CA 92111 USA
[4] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
关键词
asthma; inhaled corticosteroids; allergist; hospitalization; specialist; emergency care;
D O I
10.1067/mai.2003.178
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background: The interrelationships between optimal inhaled corticosteroid (IC) therapy, allergy specialist care, and reduced emergency hospital care for asthma have not been well defined. Objective: We sought to evaluate the independent effectiveness of various levels of IC dispensing and allergy specialist care in reducing subsequent emergency asthma hospital use. Methods: Asthmatic patients (n = 9608) aged 3 to 64 years were identified from an electronic database of a large health maintenance organization. The outcome was any year 2000 asthma hospitalization or emergency department visit. The main predictors were at least one allergy department visit and the number of IC canisters dispensed in 1999. Analyses were adjusted for age, sex, insurance type, and asthma severity (1999 emergency asthma hospital use, P-agonist use, and oral corticosteroid use). Results: Dispensing of 7 or more canisters of ICs (odds ratio [OR], 0.64; 95% CI, 0.43-0.94) and allergy care (OR, 0.73; 95% CI, 0.55-0.97) were associated with reduced subsequent emergency asthma hospital use. More patients with allergy specialist care than those without such care received 7 or more dispensations of ICs (24.7% vs 8.3%, P <.001). When 7 or more dispensations of ICs and allergy specialist care were simultaneously included in an adjusted model, both ICs (OR, 0.68; 95% CI, 0.46-1.00) and allergy care (OR, 0.77; 95% CI, 0.58-1.02) were independently associated with a lower risk of year 2000 emergency asthma hospital care, although significance was borderline. Conclusion: Allergy care reduces emergency hospital use for asthma by increasing use of ICs but probably also has an independent effect. (J Allergy Clin Immunol 2003; 111: 503-8.).
引用
收藏
页码:503 / 508
页数:6
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