Guidelines for using in vitro methods to study the effects of phyto-oestrogens on bone

被引:6
作者
Lieberherr, M [1 ]
Cournot, G
Robins, SP
机构
[1] INRA, Lab Nutr & Secur Alimentaire, F-78350 Jouy En Josas, France
[2] Rowett Res Inst, Aberdeen AB21 9SB, Scotland
关键词
phyto-oestrogens; osteoblast; osteoclast; osteoprogenitor bone marrow cells;
D O I
10.1079/BJN2002797
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
These guidelines review the relevant literature on the way plant phyto-oestrogens act on bone and the responsiveness of different bone cell systems to phyto-oestrogenic compounds. The primary emphasis is on the experimental conditions used, the markers available for assessing osteoblast and osteoclast function, and their expected sensitivity. Finally, we assess the published results to derive some general recommendations for in vitro experiments in this area of research.
引用
收藏
页码:S59 / S73
页数:15
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