Novel approaches to map protein interactions

被引：29

作者：

Figeys, D ^{[1
]}

机构：

[1] MDS Proteom, Toronto, ON, Canada

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2003年 / 14卷 / 01期

关键词：

D O I：

10.1016/S0958-1669(02)00005-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Although we now have the sequence of the human genome at hand, we face the challenge of assigning function to the identified genes. Genes usually ascribe their function through proteins, and the role of proteins is to interact with other molecules. Therefore, if we could map the interactions of proteins we would be able to understand protein function. The challenge of mapping protein interactions is vast and many novel approaches have recently been developed for this task using molecular biology, mass spectrometry and chemiproteomic techniques.

引用

页码：119 / 125

页数：7

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