Intestinal flora and mucosal immune responses

被引:47
作者
Heller, F [1 ]
Duchmann, R [1 ]
机构
[1] Free Univ Berlin, Klinikum Benjamin Franklin, Med Klin 1, D-12200 Berlin, Germany
关键词
intestinal flora; mucosal immunity; tolerance; inflammatory bowel disease; probiotics;
D O I
10.1078/1438-4221-00246
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The normal intestinal flora and the mucosal immune system exist in close spatial proximity. A normal structure and function of both very complex systems is required for health and develops in a constant and interactive process. An abnormal host response to the normal intestinal flora leads to chronic intestinal inflammation. Probiotic bacteria may modulate the intestinal flora and the mucosal immune response and are an effective therapy for remission maintenance of ulcerative colitis and pouchitis.
引用
收藏
页码:77 / 86
页数:10
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