Plant-pathogen microevolution: Molecular basis for the origin of a fungal disease in maize

被引:57
作者
Multani, DS
Meeley, RB
Paterson, AH
Gray, J
Briggs, SP
Johal, GS
机构
[1] Univ Missouri, Dept Agron, Columbia, MO 65211 USA
[2] Pioneer Hi Bred Int Inc, Dept Biotechnol Res, Johnston, IA 50131 USA
[3] Texas A&M Univ, Dept Soil & Crop Sci, College Stn, TX 77843 USA
关键词
disease resistance genes; plant-fungal interaction; host-specific toxin; Hm1; Hm2;
D O I
10.1073/pnas.95.4.1686
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A new and severe disease of maize caused by a previously unknown fungal pathogen, Cochliobolus carbonum race 1, was first described in 1938. The molecular events that led to the sudden appearance of this disease are described in this paper. Resistance to C. carbonum race 1 was found to be widespread in maize and is conferred by a pair of unlinked duplicate genes, Hm1 and Hm2. Here, we demonstrate that resistance is the wild-type condition in maize. Two events, a transposon insertion in Hm1 and a deletion in Hm2, led to the loss of resistance, resulting in the origin of a new disease. None of the other plant species tested is susceptible to C. carbonum race 1, and they all possess candidate genes with high homology to Hm1 and Hm2. In sorghum and rice, these homologs map to two chromosomal regions that are syntenic with the maize Hm1 and Hm2 loci, indicating that they are related to the maize genes by vertical descent. These results suggest that the Hm-encoded resistance is of ancient origin and probably is conserved in all grasses.
引用
收藏
页码:1686 / 1691
页数:6
相关论文
共 39 条
[1]   HOMOEOLOGOUS RELATIONSHIPS OF RICE, WHEAT AND MAIZE CHROMOSOMES [J].
AHN, S ;
ANDERSON, JA ;
SORRELLS, ME ;
TANKSLEY, SD .
MOLECULAR & GENERAL GENETICS, 1993, 241 (5-6) :483-490
[2]   COMPARATIVE LINKAGE MAPS OF THE RICE AND MAIZE GENOMES [J].
AHN, S ;
TANKSLEY, SD .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (17) :7980-7984
[3]   GRASSES AS A SINGLE GENETIC SYSTEM - GENOME COMPOSITION, COLLINEARITY AND COMPATIBILITY [J].
BENNETZEN, JL ;
FREELING, M .
TRENDS IN GENETICS, 1993, 9 (08) :259-261
[4]   INHIBITION OF MAIZE HISTONE DEACETYLASES BY HC TOXIN, THE HOST-SELECTIVE TOXIN OF COCHLIOBOLUS-CARBONUM [J].
BROSCH, G ;
RAMSOM, R ;
LECHNER, T ;
WALTON, JD ;
LOIDL, P .
PLANT CELL, 1995, 7 (11) :1941-1950
[5]   MOBILE INVERTED-REPEAT ELEMENTS OF THE TOURIST FAMILY ARE ASSOCIATED WITH THE GENES OF MANY CEREAL GRASSES [J].
BUREAU, TE ;
WESSLER, SR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (04) :1411-1415
[6]  
Coe Edward H. Jr., 1993, P157
[7]   ROLE OF HOST-SELECTIVE TOXIN IN COLONIZATION OF CORN LEAVES BY HELMINTHOSPORIUM-CARBONUM [J].
COMSTOCK, JC ;
SCHEFFER, RP .
PHYTOPATHOLOGY, 1973, 63 (01) :24-29
[8]  
Crane V, 1996, BIOLOGY OF PLANT-MICROBE INTERACTIONS, P223
[9]  
Dellaporta S.L., 1983, Plant Molecular Biology Reporter, V1, P19, DOI DOI 10.1007/BF02712670
[10]  
Gerdes JT, 1993, Compilation of North American Maize Breeding Germplasm