Radionuclide imaging metabolic activity of brown adipose tissue in a patient with pheochromocytoma

被引：32

作者：

Fukuchi, K

Tatsumi, M

Ishida, Y

Oku, N

Hatazawa, J

Wahl, RL

机构：

[1] Natl Cardiovasc Ctr, Dept Radiol, Suita, Osaka 5658565, Japan

[2] Johns Hopkins Med Inst, Dept Radiol, Div Nucl Med, Baltimore, MD USA

[3] Osaka Univ, Grad Sch Med, Div Tracer Kinet, Osaka, Japan

来源：

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES | 2004年 / 112卷 / 10期

关键词：

fat; pheochromocytoma; radionuclide imaging; positron emission tomography (PET);

D O I：

10.1055/s-2004-830407

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a patient with extra-adrenal pheochromocytoma and high plasma norepinephrine levels. Radionuclide images of this patient obtained using F-18-fluorodeoxyglucose and I-123-metaiodobenzylguanidine revealed bilateral tracer accumulation in the shoulder and lower neck. The regions of radiotracer uptake corresponded to the location of human brown adipose tissue (BAT). Excessive sympathetic stimulation by high circulating catecholamine concentrations augmented the metabolic activity and tracer uptake in the BAT. This study showed that radio-nuclide imaging can noninvasively visualize human BAT in terms of metabolic and functional activity.

引用

页码：601 / 603

页数：3

共 12 条

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