Hepatic regulation of apolipoprotein B

被引:27
作者
Avramoglu, RK [1 ]
Adeli, K [1 ]
机构
[1] Univ Toronto, Hosp Sick Children, Dept Lab Med & Pathobiol, Div Clin Biochem, Toronto, ON M5G 1X8, Canada
关键词
apolipoprotein B; VLDL; liver; dyslipidemia; insulin resistance;
D O I
10.1023/B:REMD.0000045100.66675.92
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:293 / 301
页数:9
相关论文
共 84 条
[1]   Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance [J].
Adeli, K ;
Taghibiglou, C ;
Van Iderstine, SC ;
Lewis, GF .
TRENDS IN CARDIOVASCULAR MEDICINE, 2001, 11 (05) :170-176
[2]   Apolipoprotein B is intracellularly associated with an ER-60 protease homologue in HepG2 cells [J].
Adeli, K ;
Macri, J ;
Mohammadi, A ;
Kito, M ;
Urade, R ;
Cavallo, D .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (36) :22489-22494
[3]   ADP-ribosylation factor 1 and its activation of phospholipase D are important for the assembly of very low density lipoproteins [J].
Asp, L ;
Claesson, C ;
Borén, J ;
Olofsson, SO .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (34) :26285-26292
[4]   Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells -: Roles of MAPKerk and MAPKp38 [J].
Au, WS ;
Kung, HF ;
Lin, MC .
DIABETES, 2003, 52 (05) :1073-1080
[5]   Mechanisms of metabolic dyslipidemia in insulin resistant states: Deregulation of hepatic and intestinal lipoprotein secretion [J].
Avramoglu, RK ;
Qiu, W ;
Adeli, K .
FRONTIERS IN BIOSCIENCE, 2003, 8 :D464-D476
[6]   Hepatic expression of microsomal triglyceride transfer protein and in vivo secretion of triglyceride-rich lipoproteins are increased in obese diabetic mice [J].
Bartels, ED ;
Lauritsen, M ;
Nielsen, LB .
DIABETES, 2002, 51 (04) :1233-1239
[7]   Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation [J].
Borradaile, NM ;
de Dreu, LE ;
Huff, MW .
DIABETES, 2003, 52 (10) :2554-2561
[8]   Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster [J].
Carpentier, A ;
Taghibiglou, C ;
Leung, N ;
Szeto, L ;
Van Iderstine, SC ;
Uffelman, KD ;
Buckingham, R ;
Adeli, K ;
Lewis, GF .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (32) :28795-28802
[9]   Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to ApoB in the Sec61 complex [J].
Chen, Y ;
Le Cahérec, F ;
Chuck, SL .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (19) :11887-11894
[10]   Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview [J].
Day, DA ;
Tuite, MF .
JOURNAL OF ENDOCRINOLOGY, 1998, 157 (03) :361-371