Nerve growth factor delivery systems

被引：29

作者：

Haller, MF ^{[1
]}

Saltzman, WM ^{[1
]}

机构：

[1] Cornell Univ, Sch Chem Engn, Ithaca, NY 14853 USA

来源：

JOURNAL OF CONTROLLED RELEASE | 1998年 / 53卷 / 1-3期

关键词：

controlled release; polymer; growth factors; nerve growth factor; epidermal growth factor; morphogen; cell transplantation; Alzheimer's disease;

D O I：

10.1016/S0168-3659(97)00232-0

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Growth factors encourage tissue regeneration and differentiation, accelerate wound healing, and modulate neural repair. Thus, growth factor administration may become a useful treatment for neurodegenerative diseases, such as Alzheimer's disease or Parkinson's disease, which are characterized by the degeneration of neuronal cell populations. Controlled-release polymer delivery systems may be an important technology in enabling the prevention of neuronal degeneration, or even the stimulation of neuronal regeneration, by providing a sustained release of growth factors to promote the long-term survival of endogenous or transplanted cells. (C) 1998 Elsevier Science B.V.

引用

页码：1 / 6

页数：6

共 55 条

[1] GROWTH-FACTORS AND CANCER [J].