Anorectic drugs and valvular heart disease: A biological and clinical perspective

被引:9
作者
Wong, J [1 ]
Reddy, SSK [1 ]
Klein, AL [1 ]
机构
[1] Cleveland Clin Fdn, Dept Cardiol, Cardiovasc Imaging Lab, Cleveland, OH 44195 USA
关键词
D O I
10.3949/ccjm.65.1.35
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The epidemiologic and pathologic evidence that fenfluramine and related drugs cause valvular heart disease is still speculative. However, at present, there is no alternative explanation for the cases of valvular disease found in patients taking these drugs, and there is evidence that similar substances can cause similar lesions. The manufacturer of fenfluramine and dexfenfluramine has prudently removed them from sale pending further studies.
引用
收藏
页码:35 / 41
页数:7
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