Biosensors and multiple mycotoxin analysis

被引:161
作者
van der Gaag, B [1 ]
Spath, S [1 ]
Dietrich, H [1 ]
Stigter, E [1 ]
Boonzaaijer, G [1 ]
van Osenbruggen, T [1 ]
Koopal, K [1 ]
机构
[1] TNO, Nutr & Food Res, Sensor Technol Dept, NL-3700 AJ Zeist, Netherlands
关键词
D O I
10.1016/S0956-7135(03)00008-2
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
An immunochemical biosensor assay for the detection of multiple mycotoxins in a sample is described. The inhibition assay is designed to measure four different mycotoxins in a single measurement, following extraction, sample clean-up and incubation with an appropriate cocktail of anti-mycotoxin antibodies. The different mycotoxins could be detected simultaneously in relevant concentrations within a time frame of 25 minutes, including the time needed for sensor regeneration. The application of the developed assay on presently available miniature SPR devices allows the development for low-cost instruments, which can be used in field measurements. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:251 / 254
页数:4
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