Polarization-resolved second-harmonic-generation optical coherence tomography in collagen

被引：42

作者：

Applegate, BE ^{[1
]}

Yang, CH

Rollins, AM

Izatt, JA

机构：

[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA

[2] Case Western Reserve Univ, Dept Biomed Engn, Cleveland, OH 44106 USA

来源：

OPTICS LETTERS | 2004年 / 29卷 / 19期

关键词：

D O I：

10.1364/OL.29.002252

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We describe a novel imaging technique, second-harmonic-generation optical coherence tomography (SHOCT). This technique combines the spatial resolution and depth penetration of optical coherence tomography (OCT) with the molecular sensitivity of second-harmonic-generation spectroscopy. As a consequence of the coherent detection required for OCT, polarization,resolved images arise naturally. We demonstrate this new technique on a skin sample from the belly of Icelandic salmon, acquiring polarization-resolved SHOCT and OCT images simultaneously. (C) 2004 Optical Society of America.

引用

页码：2252 / 2254

页数：3

共 8 条

[1] Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms [J].