4th ESO-ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4)

被引：864

作者：

Cardoso, F. ^{[1
,2
]}

Senkus, E. ^{[3
,4
]}

Costa, A. ^{[5
]}

Papadopoulos, E. ^{[6
]}

Aapro, M. ^{[7
]}

Andre, F. ^{[8
]}

Harbeck, N. ^{[9
]}

Aguilar Lopez, B. ^{[10
]}

Barrios, C. H. ^{[11
]}

Bergh, J. ^{[12
,13
]}

Biganzoli, L. ^{[14
,15
]}

Boers-Doers, C. B. ^{[16
]}

Cardoso, M. J. ^{[2
,17
]}

Carey, L. A. ^{[18
]}

Cortes, J. ^{[19
]}

Curigliano, G. ^{[20
]}

Dieras, V. ^{[21
]}

El Saghir, N. S. ^{[22
]}

Eniu, A. ^{[23
]}

Fallowfield, L. ^{[24
]}

Francis, P. A. ^{[25
]}

Gelmon, K. ^{[26
]}

Johnston, S. R. D. ^{[27
]}

Kaufmann, B. ^{[28
]}

Koppikar, S. ^{[29
]}

Krop, I. E. ^{[30
]}

Mayer, M. ^{[31
]}

Nakigudde, G. ^{[32
]}

Offersen, B. V. ^{[33
,34
,35
]}

Ohno, S. ^{[36
]}

Pagani, O. ^{[37
]}

Paluch-Shimon, S. ^{[38
]}

Penault-Llorca, F. ^{[39
]}

Prat, A. ^{[40
]}

Rugo, H. S. ^{[41
]}

Sledge, G. W. ^{[42
]}

Spence, D. ^{[43
]}

Thomssen, C. ^{[44
]}

Vorobiof, D. A. ^{[45
]}

Xu, B. ^{[46
]}

Norton, L. ^{[47
]}

Winer, E. P. ^{[48
]}

机构：

[1] ESMO, ESO, Lisbon, Portugal

[2] Champalimaud Fdn, Champalimaud Clin Ctr, Breast Unit, Lisbon, Portugal

[3] ESMO, Gdansk, Poland

[4] Med Univ Gdansk, Dept Radiotherapy & Oncol, Gdansk, Poland

[5] European Sch Oncol, Milan, Italy

[6] Europa Donna Cyprus, Nicosia, Cyprus

[7] Clin Genolier, Dept Oncol, Genolier, Switzerland

[8] Inst Gustave Roussy, Dept Med Oncol, Villejuif, France

[9] Univ Munich LMU, Dept Obstet & Gynaecol, Breast Ctr, Munich, Germany

[10] ULACCAM Union Latinoamer Canc Mujer, Direct Off, Mexico City, DF, Mexico

[11] PURCS Sch Med, Dept Oncol, Porto Alegre, RS, Brazil

[12] Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden

[13] Univ Hosp, Stockholm, Sweden

[14] European Soc Breast Canc Specialists EUSOMA, Prato, Italy

[15] Nuovo Osped Prato, Dept Med Oncol, Ist Toscano Tumori, Prato, Italy

[16] CB Boers Org, Wormer, Netherlands

[17] Nova Med Sch, Lisbon, Portugal

[18] UNC, Dept Hematol & Oncol, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA

[19] Vall dHebron Univ, Dept Oncol, Barcelona, Spain

[20] Univ Milan, European Inst Oncol, Dept Oncol & Hematooncol, Div Early Drug Dev, Milan, Italy

[21] Ctr Eugene Marquis, Gynaecol & Breast Dept, Rennes, France

[22] Amer Univ Beirut, Breast Ctr Excellence, Med Ctr, Beirut, Lebanon

[23] Canc Inst Ion Chiricuta, Breast Canc Dept, Cluj Napoca, Romania

[24] Univ Sussex, Brighton & Sussex Med Sch, SHORE C, Brighton, E Sussex, England

[25] Peter MacCallum Canc Ctr, Div Canc Med, Melbourne, Vic, Australia

[26] BC Canc Agcy, Med Oncol Dept, Vancouver, BC, Canada

[27] Royal Marsden, Dept Med, Sutton, Surrey, England

[28] Sheba Med Ctr, Dept Oncol, Ramat Gan, Israel

[29] Bombay Hosp Inst Med Sci, Dept Med Oncol, Bombay, Maharashtra, India

[30] Dana Farber Canc Inst, Breast Oncol Ctr, Boston, MA 02115 USA

[31] Adv BCorg, New York, NY USA

[32] UWOCASO Uganda Womens Canc Support Org, Advocacy Dept, Kampala, Uganda

[33] European Soc Radiat Oncol ESTRO, Aarhus, Denmark

[34] Aarhus Univ Hosp, Dept Expt Clin Oncol, Aarhus, Denmark

[35] Aarhus Univ Hosp, Dept Oncol, Aarhus, Denmark

[36] Canc Inst Hosp, Breast Oncol Ctr, Tokyo, Japan

[37] Geneva Univ Hosp, Inst Oncol Southern Switzerland, Swiss Grp Clin Canc Res SAKK, IBCSG, Bellinzona, Switzerland

[38] Shaare Zedek Med Ctr, Inst Oncol, Jerusalem, Israel

[39] Ctr Jean Perrin, Dept Pathol, Clermont Ferrand, France

[40] Hosp Clin Barcelona, IDIBAPS, Translat Genom & Targeted Therapeut Solid Tumor, Barcelona, Spain

[41] UCSF, Breast Oncol Clin Trials Educ, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[42] Stanford Univ, Med Ctr, Oncol Div, Stanford, CA 94305 USA

[43] Breast Canc Network Australia, Policy Dept, Camberwell, Vic, Australia

[44] Martin Luther Univ Halle Wittenburg, Dept Gynaecol, Halle, Germany

[45] Sandton Oncol Ctr, Dept Oncol, Johannesburg, South Africa

[46] Chinese Acad Med Sci, Dept Med Oncol, Canc Hosp, Beijing, Peoples R China

[47] Mem Sloan Kettering Canc Ctr, Breast Canc Med Serv, 1275 York Ave, New York, NY 10021 USA

[48] Dana Farber Canc Inst, Susan Smith Ctr Womens Canc, Breast Oncol Ctr, Boston, MA 02115 USA

来源：

ANNALS OF ONCOLOGY | 2018年 / 29卷 / 08期

关键词：

breast cancer; metastatic; advanced; guidelines; ABC; ESO-ESMO; QUALITY-OF-LIFE; PHASE-II TRIAL; DOUBLE-BLIND; FERTILITY PRESERVATION; RADIATION NECROSIS; OPEN-LABEL; SURVIVAL; COMBINATION; PALBOCICLIB; FULVESTRANT;

D O I：

10.1093/annonc/mdy192

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Advanced Breast Cancer (ABC) comprises both locally advanced breast cancer (LABC) and metastatic breast cancer (MBC) [1]. Although treatable, MBC remains virtually an incurable disease with a median overall survival (OS) of 3 years and a 5-year survival of only 25% [2, 3]. The MBC Decade Report [2] shows that progress has been slow in terms of improved outcomes, quality of life (QoL), awareness and information regarding ABC. More recently, some studies seem to indicate an improvement in OS, mostly due to advances in human epidermal growth factor receptor 2 (HER2)-positive ABC [4-6]. The better survival is seen in an environment with access to the best available care and particularly in de novo ABC, while recurrent ABC seems to become harder to manage [7, 8]. © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society for Medical Oncology.

引用

页码：1634 / 1657

页数：24

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