Structural insight into the binding motifs for the calcium ion and the non-catalytic zinc in matrix metalloproteases

被引：21

作者：

Massova, I ^{[1
]}

Kotra, LP ^{[1
]}

Mobashery, S ^{[1
]}

机构：

[1] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 07期

关键词：

D O I：

10.1016/S0960-894X(98)00128-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The binding motifs for the structural zinc and calcium ions in matrix metalloproteases (MMPs) were investigated by analyzing the three-dimensional structural models of 23 representative MMPs. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：853 / 858

页数：6

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