Highly regio- and stereoselective four-component iodoamination of Se-substituted allenes.: an efficient synthesis of N-(3-organoseleno-2-iodo-2(Z)-propenyl) acetamides

被引：42

作者：

Ma, SM ^{[1
]}

Hao, XS

Huang, X

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 09期

关键词：

D O I：

10.1039/b300879g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Z-Selectivity was observed for iodohydroxylation of Se-substituted allenes with I-2 and H2O, which is opposite to that of 1,2-allenyl sulfoxides. With n-hexane as the co-solvent Z-iodoamination leading to N-(3-organoseleno-2-iodo-2(Z)propenyl)acetamide was observed. A brief rational for the stereoselectivity of this reaction is provided.

引用

页码：1082 / 1083

页数：2

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