Dendritic cells under the spell of prostaglandins

被引：52

作者：

Morelli, AE

Thomson, AW

机构：

[1] Univ Pittsburgh, Thomas E Starzl Transplantat Inst, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Dept Surg, Pittsburgh, PA 15213 USA

[3] Univ Pittsburgh, Dept Immunol, Pittsburgh, PA 15213 USA

[4] Univ Pittsburgh, Med Ctr, Pittsburgh, PA 15213 USA

来源：

TRENDS IN IMMUNOLOGY | 2003年 / 24卷 / 03期

关键词：

D O I：

10.1016/S1471-4906(03)00023-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In addition to their potential to modulate the maturation, interleukin-12 producing capacity and Th-cell-polarizing ability of dendritic cells, there is new direct evidence that prostaglandins (PGs) regulate chemokine receptor expression, cell migration and apoptosis of these important professional antigen-presenting cells. We discuss these new insights in relation to how PGs might influence innate and adaptive immune responses.

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收藏

页码：108 / 111

页数：4

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