New amidino-benzimidazolyl thiophenes: Synthesis and photochemical synthesis

被引：15

作者：

Starcevic, K

Boykin, DW

Karminski-Zamola, G ^{[1
]}

机构：

[1] Univ Zagreb, Fac Chem Engn & Technol, Dept Organ Chem, Zagreb 10000, Croatia

[2] Georgia State Univ, Dept Chem, Atlanta, GA 30303 USA

[3] Georgia State Univ, Ctr Biotechnol & Drug Design, Atlanta, GA 30303 USA

来源：

HETEROATOM CHEMISTRY | 2003年 / 14卷 / 03期

关键词：

D O I：

10.1002/hc.10126

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New amidino-benzimidazolyl-substituted bis-1,2-(2-thienyl)ethenes (4, 5, and 6) and benzo[1,2-b:4,3-b']dithiophenes (8, 9, and 10) were prepared by the condensation of amidino-substituted o-phenylene diamines with corresponding dialdehydes (3 and 7). All prepared amidino-benzimidazolylsubstituted compounds are of particular interest, because they can serve as intercalators or groove binders on DNA in anticancer therapy. (C) 2003 Wiley Periodicals, Inc.

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页码：218 / 222

页数：5

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