Model identification of batch precipitations: application to salicylic acid

被引：13

作者：

Nallet, V ^{[1
]}

Mangin, D ^{[1
]}

Klein, JP ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, Lab Automat & GEnie Proc, LAGEP,UPRESA Q5007,ESCPE Lyon, F-69622 Villeurbanne, France

来源：

COMPUTERS & CHEMICAL ENGINEERING | 1998年 / 22卷

关键词：

precipitation; population balance; modelling; nucleation kinetics; crystal growth kinetics;

D O I：

10.1016/S0098-1354(98)00116-1

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

Batch precipitations of salicylic acid are modelled in order to determine the kinetics of the different crystallization mechanisms. The population balance equation, relating the crystal size distribution (CSD), is discretized and solved with the method of classes. Primary and secondary nucleations and chemical and diffusion controlled growth are taken into account. The model, which involves six kinetic parameters, was fitted to the measured supersaturation profiles and the final CSDs of three experiments by numerical optimization. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：S649 / S652

页数：4

共 10 条

[1] A NEW METHOD OF CONSTRAINED OPTIMIZATION AND A COMPARISON WITH OTHER METHODS [J].