Synthesis, characterization, antibacterial and antiproliferative activities of monodisperse chitosan- based silver nanoparticles

被引：141

作者：

Hoang Vinh Tran ^{[2
]}

Lam Dai Tran ^{[1
]}

Cham Thi Ba ^{[3
]}

Hoang Dinh Vu ^{[2
]}

Thinh Ngoc Nguyen ^{[2
]}

Dien Gia Pham ^{[3
]}

Phuc Xuan Nguyen ^{[1
]}

机构：

[1] Vietnamese Acad Sci & Technol, Inst Mat Sci, Hanoi, Vietnam

[2] Hanoi Univ Technol, Fac Chem Technol, Hanoi, Vietnam

[3] Vietnamese Acad Sci & Technol, Inst Chem, Hanoi, Vietnam

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2010年 / 360卷 / 1-3期

关键词：

Silver nanoparticles (AgNPs); Chitosan (CS); Kinetics; Antibacterial and antiproliferative activities; REDUCTION; METAL; GOLD; AG+;

D O I：

10.1016/j.colsurfa.2010.02.007

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Silver nanoparticles (AgNPs) have been known to have inhibitory and bactericidal effects In this paper we investigated. (i) the synthesis and kinetics of finely dispersed AgNPs in a biocompatible chitosan-derived polysaccharide solution, (ii) the antibacterial activities toward both gram (Escherichia colt and Pseudomonas aeruginosa) and gram(+) bacteria (Lactobacillus fermentum. Staphylococcus aureus and Bacillus subtilis) and yeast (Candida albicans) of the obtained AgNPs, and (in) in vitro cytotoxicity against HepG2 (hepatocellular carcinoma), Lu (human lung carcinoma), KB (human epidermic carcinoma), MCF-7 (human breast carcinoma) cancer cell lines. The samples demonstrated considerably high antibacterial and antiproliferative activities against above bacterial strains and cell lines, which can be explained on the basis of finely and homogenously dispersed nanoparticles. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：32 / 40

页数：9

共 18 条

[1] Synthesis and UV-vis spectroscopic study of silver nanoparticles in aqueous SDS solution [J].

Bhui, Dipak Kumar ;

Bar, Harekrishna ;

Sarkar, Priyanka ;

Sahoo, Gobinda Prasad ;

De, Sankar Prasad ;

Misra, Ajay .

JOURNAL OF MOLECULAR LIQUIDS, 2009, 145 (01) :33-37

[2] Polyol Synthesis of Silver Nanoparticles: Mechanism of Reduction by Alditol Bearing Polysaccharides [J].

Donati, Ivan ;

Travan, Andrea ;

Pelillo, Chiara ;

Scarpa, Tommaso ;

Coslovi, Anna ;

Bonifacio, Alois ;

Sergo, Valter ;

Paoletti, Sergio .

BIOMACROMOLECULES, 2009, 10 (02) :210-213

[3] Time-resolved investigation of early processes in the reduction of Ag+ on polyacrylate in aqueous solution [J].

Ershov, BG ;

Henglein, A .

JOURNAL OF PHYSICAL CHEMISTRY B, 1998, 102 (52) :10667-10671

[4]

FRESNEY RI, 1993, MANUAL BASIS TECHNIQ

[5] Synthesis of polysaccharide-stabilized gold and silver nanoparticles: a green method [J].

Huang, HZ ;

Yang, XR .

CARBOHYDRATE RESEARCH, 2004, 339 (15) :2627-2631

[6] Preparation and characterization of metal-chitosan nanocomposites [J].

Huang, HZ ;

Yuan, Q ;

Yang, XR .

COLLOIDS AND SURFACES B-BIOINTERFACES, 2004, 39 (1-2) :31-37

[7] Exploitation of localized surface plasmon resonance [J].

Hutter, E ;

Fendler, JH .

ADVANCED MATERIALS, 2004, 16 (19) :1685-1706

[8] STRUCTURE OF A VERY SMALL PIECE OF SILVER METAL - OCTAHEDRAL AG6 MOLECULE, 2 CRYSTAL-STRUCTURES OF PARTIALLY DECOMPOSED VACUUM-DEHYDRATED FULLY AG+-EXCHANGED ZEOLITE-A [J].

KIM, Y ;

SEFF, K .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (21) :7055-7057

[9]

Kumar MNVR, 2000, REACT FUNCT POLYM, V46, P1

[10]

Lam TD., 2006, J Chem, V44, P105

← 1 2 →