A synthetic tripeptide as a novel organo-gelator: a structural investigation

被引：41

作者：

Maji, SK

Malik, S

Drew, MGB

Nandi, AK ^{[2
]}

Banerjee, A

机构：

[1] Indian Assoc Cultivat Sci, Dept Biol Chem, Kolkata 700032, W Bengal, India

[2] Indian Assoc Cultivat Sci, Polymer Sci Unit, Kolkata 700032, W Bengal, India

[3] Univ Reading, Dept Chem, Reading RG6 6AD, Berks, England

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 21期

基金：

英国工程与自然科学研究理事会;

关键词：

organogelator; Aib; synthetic peptide;

D O I：

10.1016/S0040-4039(03)00839-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A self-associating synthetic tripeptide [Boc-Ala(1)-Aib(2)-beta-Ala(3)-OMe (Aib: alpha-amino-isobutyric acid, beta-Ala: beta-alanine)] forms thermoreversible transparent gels in various organic solvents and this offers the first example of a peptide gelator whose molecular self-assembly afforded for gelation has been characterised by single-crystal X-ray diffraction and FT-IR and NMR spectroscopic studies. The crystal structure of an analogous synthetic non-gelator tripeptide [Boc-Ala(1)-Gly(2)-beta-Ala(3)-OMe] is also discussed in light of the self-assembly of the gelator tripeptide. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：4103 / 4107

页数：5

共 40 条

[1] The quest for the simplest possible organogelators and some properties of their organogels [J].