Parkinson disease gene therapy moves toward the clinic

被引：35

作者：

Björklund, A ^{[1
]}

Lindvall, O ^{[1
]}

机构：

[1] Univ Lund, Wallenberg Neurosci Ctr, S-22362 Lund, Sweden

来源：

NATURE MEDICINE | 2000年 / 6卷 / 11期

关键词：

D O I：

10.1038/81291

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Current therapies for Parkinson disease focus mainly on symptomatic relief, but gene therapy approaches may offer the prospect of halting or reversing the progress of the disease process itself. A recent study provides evidence that sustained delivery of glial cell line-derived neurotrophic factor to the nigrostriatal system provides neuroprotection and functional recovery in a primate model of Parkinson disease.

引用

页码：1207 / 1208

页数：2

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