Sleep apnea in the elderly:: A specific entity?

被引:92
作者
Launois, Sandrine H.
Pepin, Jean-Louis
Levy, Patrick
机构
[1] Univ Grenoble 1, INSERM, HP2 Lab, F-38041 Grenoble, France
[2] Ctr Hosp Univ, Sleep Lab, Grenoble, France
关键词
elderly; obstructive sleep apnea; central sleep apnea; continuous positive airway pressure;
D O I
10.1016/j.smrv.2006.08.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Steep apnea is highly prevalent in subjects after age 60, and affects older men and women similarly. Central apneas are often observed in addition to obstructive and mixed events. Pathogenesis of obstructive and central events during steep in the elderly can be attributed to an amplification of well-established causes of steep-disordered breathing (SDB) in younger adults. As in middle-aged adults, sleep-retated complaints, cardiovascular diseases, depression and traffic accidents should prompt an evaluation by a steep specialist. However, secondary enuresis and nocturia, cognitive impairment, ophthalmic conditions and repeated falls may be the main complaint in elderly subjects. Steep studies in the elderly should systematically include reliable means to detect central apneas and periodic leg movements. Untreated SDB in the elderly appears to have a lesser impact on mortality than in middle-aged adults. However, the typical morbidity associated with the disorder in younger adults is observed in the elderly. Elderly symptomatic SDB patients tolerate CPAP no differently than younger patients and should be effectively treated. In conclusion, whether steep apnea in the elderly represents a specific entity or the same disease as in younger subjects, with some distinctive features, is still unclear. Further research, in particular focusing on the impact of age on SDB outcomes, is needed. (C) 2006 Elsevier Ltd. All. rights reserved.
引用
收藏
页码:87 / 97
页数:11
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