Renal manifestations of the antiphospholipid syndrome

被引:23
作者
D'Cruz, DP [1 ]
机构
[1] St Thomas Hosp, Rayne Inst, Lupus Res Unit, London SE1 7EH, England
关键词
antiphospholipid ( Hughes) syndrome; hypertension; renal artery stenosis; renal transplantation; renal vascular thrombosis; thrombotic microangiopathy;
D O I
10.1191/0961203305lu2058oa
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Renal thrombotic manifestations have been reported since the earliest descriptions of the antiphospholipid (Hughes) syndrome (APS). The spectrum of clinical features associated with antiphospholipid nephropathy continues to widen. This review will highlight recent developments such as the prevalence of hypertension, livedo reticularis and renal artery stenosis as well as the ultrastructural changes seen in antiphospholipid nephropathy. The increasing risks of renal transplantation in antiphospholipid antibody positive patients is also discussed leading some authors to question whether these patients should undergo transplantation at all.
引用
收藏
页码:45 / 48
页数:4
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