Purification of an extracellular signaling molecule involved in production of aerial mycelium by Streptomyces coelicolor

被引：69

作者：

Nodwell, JR ^{[1
]}

Losick, R ^{[1
]}

机构：

[1] Harvard Univ, Biol Labs, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA

来源：

JOURNAL OF BACTERIOLOGY | 1998年 / 180卷 / 05期

关键词：

D O I：

10.1128/JB.180.5.1334-1337.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have extensively purified a factor from conditioned medium that restores aerial mycelium formation to a mutant of Streptomyces coelicolor that is defective in morphological differentiation. Response to this factor is shown to depend on the presence of the BIdK oligopeptide import system. We suggest that this substance acts at the first step in a putative cascade of developmental regulatory signals.

引用

页码：1334 / 1337

页数：4

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