Regression of dilated-hypokinetic hypertrophic cardiomyopathy by biventricular cardiac pacing

被引:16
作者
Ashrafian, Houman [1 ]
Mason, Mark J. [1 ]
Mitchell, Andrew G. [1 ]
机构
[1] Harefield Hosp, Dept Cardiol, Royal Brompton & Harefield NHS Trust, Harefield UB9 6JH, Middx, England
来源
EUROPACE | 2007年 / 9卷 / 01期
关键词
dilated-hypokinetic; hypertrophic cardiomyopathy; cardiac resynchronization therapy; biventricular pacing;
D O I
10.1093/europace/eul137
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The evolution of hypertrophic cardiomyopathy (HCM) towards dilatation and hypokinesis is an increasingly recognized complication with a high incidence of adverse outcomes, including sudden cardiac death, requiring defibrillator implantation and cardiac transplantation. It is generally regarded as the irreversible 'burnt-out' end-stage manifestation of HCM. We report one of the first cases of profound regression of the ditated-hypokinetic state by the application of biventricular pacing and cardiac resynchronization therapy (CRT). Reviewing the literature on the role of pacing in HCM and the energetic rationale for CRT in HCM prompts us to suggest that further systematic studies are needed urgently to assess the role of CRT in HCM variants.
引用
收藏
页码:50 / 54
页数:5
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