Split personalities: the agonistic antagonist Sprouty

被引：73

作者：

Christofori, G ^{[1
]}

机构：

[1] Univ Basel, Dept Clin Biol Sci, Inst Biochem & Genet, CH-4051 Basel, Switzerland

来源：

NATURE CELL BIOLOGY | 2003年 / 5卷 / 05期

关键词：

D O I：

10.1038/ncb0503-377

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

Sprouty proteins are antagonists of receptor tyrosine kinase (RTK) signalling in a number of developmental and physiological processes. A collection of work indicates that Sprouty proteins negatively and positively modulate RTK-induced signalling pathways through various mechanisms, thereby combining a variety of cellular functions in one molecule.

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页码：377 / 379

页数：3

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