Treatment of choroidal melanoma using photodynamic therapy

被引：59

作者：

Barbazetto, IA

Lee, TC

Rollins, IS

Chang, S

Abramson, DH

机构：

[1] Columbia Presbyterian Med Ctr, ES Harkness Eye Inst, New York, NY 10032 USA

[2] Columbia Univ, New York Presbyterian Hosp, New York, NY USA

[3] Weill Cornell Univ, New York Presbyterian Hosp, Dept Ophthalmol, New York, NY USA

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 2003年 / 135卷 / 06期

关键词：

D O I：

10.1016/S0002-9394(02)02222-5

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PURPOSE: To investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma. DESIGN: Interventional case series. METHODS: Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary thermotherapy were treated with photodynamic therapy. RESULTS: One tumor decreased in size and remained stable for 18 months. One tumor had no growth for I I months. Two melanomas continued to grow, necessitating enucleation. CONCLUSION: Of the four eyes that had failed conventional therapies, two would have been salvaged (to date) with photodynamic therapy. However, additional studies are needed to determine if photodynamic therapy can play a role in the management of choroidal melanoma. (C) 2003 by Elsevier Inc. All rights reserved.

引用

页码：898 / 899

页数：2