Do circulating cytokines really matter in sepsis?

被引：21

作者：

Tetta, C

Bellomo, R

D'Intini, V

De Nitti, C

Inguaggiato, P

Brendolan, A

Ronco, C

机构：

[1] Fresenius Med Care, Renal Res, Div Med, D-61352 Bad Homburg, Germany

[2] Austin & Repatriat Med Ctr, Dept Intens Care, Melbourne, Vic, Australia

[3] St Bortolo Hosp, Dept Nephrol, Vicenza, Italy

来源：

KIDNEY INTERNATIONAL | 2003年 / 63卷

关键词：

sepsis; septic shock; cytokines; endotoxin; LPS; hemofiltration; plasmapheresis; adsorption; multiorgan failure; plasma filtration;

D O I：

10.1046/j.1523-1755.63.s84.40.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Sepsis remains the major cause of mortality worldwide, claiming millions of lives each year. The past decade has seen major advances in the understanding of the biological mechanisms involved in this complex process. Unfortunately, no definitive therapy yet exists that can successfully treat sepsis and its complications. In this review, we will address the significance of circulating cytokines in the pathophysiology of sepsis and its relevance to new approaches in extracorporeal therapies.

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收藏

页码：S69 / S71

页数：3

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