Antiphase oscillation of the left and right suprachiasmatic nuclei

被引：231

作者：

de la Iglesia, HO ^{[1
]}

Meyer, J ^{[1
]}

Carpino, A ^{[1
]}

Schwartz, WJ ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Neurol, Worcester, MA 01655 USA

来源：

SCIENCE | 2000年 / 290卷 / 5492期

关键词：

D O I：

10.1126/science.290.5492.799

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An unusual property of the circadian timekeeping systems of animals is rhythm "splitting," in which a single daily period of physical activity (usually measured as wheel running) dissociates into two stably coupled components about 12 hours apart; this behavior has been ascribed to a clock composed of two circadian oscillators cycling in antiphase. We analyzed gene expression in the hypothalamic circadian clock, the suprachiasmatic nucleus (SCN), of behaviorally "split" hamsters housed in constant Light. The results show that the two oscillators underlying the split condition correspond to the Left and right sides of the bilaterally paired SCN.

引用

页码：799 / 801

页数：3

共 37 条

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