Nordehydrocyclodercitin, a hexacyclic pyridoacridine alkaloid from the marine ascidian, Aplidium sp.

被引:14
作者
Agrawal, Madhavi S. [1 ]
Bowden, Bruce F. [1 ]
机构
[1] James Cook Univ N Queensland, Sch Pharm & Mol Sci, Townsville, Qld 4811, Australia
基金
日本学术振兴会;
关键词
pyridoacridine; cyclodercitin; stellettamine; cycloshermilamine; aplidium;
D O I
10.1080/14786410601132212
中图分类号
O69 [应用化学];
学科分类号
081704 [应用化学];
摘要
A new hexacyclic pyridoacridine alkaloid, nordehydrocyclodercitin (1), from an ascidian, Aplidium sp., cf. Aphdium cratiferum collected at Arab Reef, Great Barrier Reef, Australia is reported. Nordehydrocyclodercitin is structurally related to stellettamine (2) and cyclodercitin (3), which are sponge metabolites, and cycloshermilamine D (4) which was isolated from the marine tunicate Cystodytes violatinctus. The structure of nordehydrocycloderci tin was determined by interpretation of spectroscopic data, particularly those obtained from HMBC correlations, and by comparison with reported data for known related pyridoacridine alkaloids.
引用
收藏
页码:782 / 786
页数:5
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